REFERENTIEL REGIONAL ONCO-LR. Comité Onco-Hématologie. Leucemie Lymphoïde Chronique B. Groupe de travail: Dr Burcheri, Dr Donadio, Dr Garrido, . kinase inhibitor (BTK) already widely used in CLL and Mantle Cell Lymphoma. All news · Our trials · Our publications. Microscope, Chercheurs, Leucémie. Leucémie lymphoïde chronique en rechute après greffe allogénique: place à l’ ibrutinib? Volume 23, issue 1, Janvier-Février · PDF; Print; Save to My.
|Country:||Sao Tome and Principe|
|Published (Last):||24 October 2009|
|PDF File Size:||5.54 Mb|
|ePub File Size:||20.37 Mb|
|Price:||Free* [*Free Regsitration Required]|
Specific cutaneous infiltrates of chronic lymphocytic leukaemia CLL are rare. CLL skin infiltrates as the primary manifestation of the disease have been reported, but a normal lymphocyte count at diagnosis is rare.
We present two cases of CLL initially presenting in the skin, without lymphocytosis. A year-old man developed papulonodular lesions of the face and infiltrated plaques of the scalp, and an year-old woman presented erythematous nodules of the face and neck.
The two patients had no lymphocytosis, but immunophenotyping was characteristic of CLL. In the second case, there was a sub-mental adenopathy, histologic analysis of which was consistent with CLL.
No disease progression was noted at follow-up.
The unusual feature of these cases is the lack of lymphocytosis at diagnosis. Thus, the skin lesions resulted in further evaluations for CLL, although the diagnosis was not suggested by the blood count. Skin involvement in CLL does lympoide appear to be a poor prognostic indicator, arguing in favour of recruitment of circulating monoclonal B-cells rather than an additional tumour mass.
Chronic lymphocytic leukaemia, Small lymphocytic lymphoma, Skin infiltration, Leukaemia cutis, Lymphocytosis. Journal page Archives Contents list. Access to the text HTML. Access to the PDF text. Access to the full text of this article requires a subscription.
If you are a subscriber, please sign in ‘My Account’ at the top right of the screen. If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: Chronic lymphocytic leukaemia presenting with specific cutaneous infiltrates in the absence of lymphocytosis: Vonarx aO. Carpentier aB. Cazin cB. Bouchindhomme dE. Outline Masquer le plan.
Knowledge. Confidence. Hope.
Top of the page – Article Outline. Contact Help Who are we?
As per the Law relating to information storage chroniqu personal integrity, you have the right to oppose art 26 of that lawaccess art 34 of that law and rectify art 36 of that law your personal data.
You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
FILO : Chronic Lymphoid Leukemia (CLL) and Waldenström’s Disease (MW)
Personal information regarding our website’s visitors, including their identity, is confidential. The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties. You can move this window by clicking on the headline.